Author(s):
1. Mirjana Janićijević, Univerzitet u Kragujevcu, Srbija, Fakultet Medicinskih Nauka,, 2. Katarina Janicijevic, Univerzitet u Kragujevcu, Srbija, Fakultet Medicinskih Nauka,, Serbia
3. Tatjana Sarenac Vulovic, Klinika za oftalmologiju KC Kragujevac, Serbia

Abstract:
Abstract Aim: To evaluate success rate (efficacy, safety) in treatment of post-chemical injuries and corneal defects using autologous serum eye drops. Material and Methods: Authors reviewed 112 patients (123 eyes) hospitalized in Clinic of ophthalmology from 2013 to 2016, who had post-causoma corneal defects that were non responsive to conventional treatment and were treated with serum therapy. Authors correlated time of epithelialisation of defects with rate of epithelial healing. Results: Authors investigated 112 patients (65 males, 47 females; aged 18-74) for treatment of corneal defects. Application of autologous serum therapy 63 (51.22%) of 123 eyes was healed in an average time of 4 weeks. Among 116 eyes, epithelial defects healed in 8 (6.50%) within 1 week, in additional 22 (17.89%) in 1-2 weeks, totaling 21 (17.07%) within 3 weeks. Six eyes (4.88%) completely healed at 5 week; two eyes (1.62%) had subsequent healing of epithelial defect at 6 week; the remaining eight eyes healed within 1.5 month. Conclusion: Using serum therapy, it was managed to reduce time of healing from eleven weeks, which were necessary just couple years ago (before 2010) to four (maximum six) weeks to complete healing which are necessary today.

Key words:
Keywords: chemical injuries,corneal defects,autologous serum,therapy

Thematic field:
Rožnjača, vežnjača

Date of abstract submission:
01.04.2017.

Conference:
Drugi kongres oftalmologa Republike Srpske sa međunarodnim učešćem

Final paper